19 Şubat 2012 Pazar

Karyotype and Chromosomal Anomaly


A karyotype test is basically a test that analyzes your chromosomes. It tells you how many chromosomes a person has and looks at the structure of each chromosome individually.

As we all know, there are different diseases that comes from chromosomal abnormality. If the number of chromosomes is less or more than the 46, it causes some problems which comes from the defects with the division of the egg or zygote. One example can be a people who has a additional chromosome in his/her 21st chromosome, in other words down syndrome. A karyotype can be done before the baby born to determine chromosome numbers of the baby. Anyway, there are two ways to do a karyotype; one is amniocentesis and the other one is Chorionic villis sampling. In order to make Amniocentesis doctors use a long needle to take out some of the liquid that surrounds the developing baby, for the Chorionic villis sampling, doctors get a sample of the cells from the 'villi' of the placenta. Both of these methods are invasive and expensive, so it's only recommended in cases when there is more likelihood of a chromosomal abnormality. For instance, doctors must decide if it's necessary to make a karyotype or not. It's not a decision that parents can make, the decision that can done by parents should be ' the abortion or not.' Doctors can only supply the results of the test and worn parents about it but the rest is all on the mother and the father's shoulders. Because they are the ones who are responsible of that baby's future. 

If I found out that my future child had a chromosomal anomaly, honestly I would made my decision on the abortion side. I would not want to give a hard life to that baby since he/she doesn't deserve such a life. The healthiest decision for me and that baby would be the abortion. Because after the first minute that child born, the whole world and people perspectives will be different on him/her, that child never get the same rights as other people. Every single person wants to give the best life for their child so i would think it's not the good life to live. Maybe it's hard to let strange people to get 'your' baby from your body just as separating a part from your body, it would be the right decision for that innocent unborn baby.



have a good week :) 




12 Şubat 2012 Pazar

If you don't know the relationship between the Sickle Cell Anemia and Malaria, IT'S TIME TO LEARN!

Let's start by watching this cute little video ( please do watch! it's only 5 minutes :)

Sickle cell disease is an inherited disorder in which red blood cells (RBCs) are abnormally shaped. This abnormality can result in painful episodes, serious infections, chronic anemia, and damage to body organs.

It gets its name because a person's red blood cells are shaped like sickles, or crescent moons, instead of their usual round, disc shape.
Round is the healthiest shape for red blood cells (or RBCs) because they can move easily through the body. RBCs carry oxygen around your body, and every part of your body needs oxygen to work properly.

Many people don't know they have sickle cell trait. When both parents have the sickle cell trait, there's a 25% chance that a child will have sickle cell disease. But when one parent is carrying the trait and the other actually has the disease, the odds increase to 50% that their offspring will inherit the disease.

This picture briefly shows the process.

Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected mosquitoes. 


The case of sickle cell anemia and malaria is an example of correlation without causation.

- ( now wait, if you are like " what is a correlation or causation!!" dont be stress, there is an little explanation for you )
Correlation: mutual relation of two or more things, parts, etc. Synonyms: similarity, correspondence,matching; parallelism.
Causation: the relation of cause  to effect; causality.-

Anyway, sickle cell anemia and malaria disease have a parallel relationship between them but one of them doesn't cause the other one. If a person inherits one copy of the sickle gene and the other being normal, this person gets advantageous than the others. Since, those who carry the sickle cell trait do not suffer nearly as severely from the disease. Also these carriers have been naturally selected, because the trait confers some resistance to malaria.


Bibliography 

"Sickle Cell Disease." KidsHealth - the Web's Most Visited Site about Children's Health. Web. 12 Feb. 2012. <http://kidshealth.org/parent/medical/heart/sickle_cell_anemia.html>.
"WHO | Malaria." Web. 12 Feb. 2012. 
<http://www.who.int/mediacentre/factsheets/fs094/en/>.
"Evolution: Library: A Mutation Story." PBS: Public Broadcasting Service. Web. 12 Feb. 2012
<http://www.pbs.org/wgbh/evolution/library/01/2/l_012_02.html>.